Monday, June 18, 2012

ALPINE RAGWORT (Senecio nemorensis L.)

ALPINE RAGWORT (Senecio nemorensis L.)


PH2 may have been confused in assigning the common names life root and squaw weed to
this species, more often reserved for American S. aureus. Some data (HHB) apply to ssp.
fuchsii.
Activities (Alpine Ragwort) — Carcinogenic (1; HHB; PH2); Hemostat (1; HHB; PH2); Hepatotoxic
(1; HHB; PH2); Hypoglycemic (1; PH2); Hypotensive (f; BRU).
Indications (Alpine Ragwort) — Bleeding (1; BRU; HHB; PH2); Diabetes (1; PH2); High
Blood Pressure (f; BRU; PH2); Hyperglycemia (1; PH2); Odontosis (f; PH2); Uterostimulant
(f; PH2).
Dosages (Alpine Ragwort) — Do not take (JAD). Steep 1 tsp 5–10 minutes in cup hot water; take
several times a day as needed (PH2). (Still, PH2 says it should not be taken internally.)
Contraindications, Interactions, and Side Effects (Alpine Ragwort) — Not covered (AHP).
Contains pyrrolizidine alkaloids (PAs) in considerable amounts and varieties, which can be
carcinogenic, hepatotoxic, and mutagenic. Use of Senecio species can result in potentially fatal
hepatic veno-occlusive disease in humans, with symptoms of abdominal pain and vomiting
with ascites. PAs are toxic to humans, with liver damage with cirrhosis and ascites, or seneciosis
(VOD) reported in almost all cases of severe or fatal intoxications, from intakes of 0.5 mg/kg
to 3.3 mg/kg (AEH).

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